Фармакология: лист заданий с ответами

Tamoxifen is used mainly to treat:

1. AOestrogen receptor-positive breast cancer
2. BOsteoarthritis
3. CType 2 diabetes
4. DProstate enlargement and prostate cancer in older men

Which drug is an antidote for methanol or ethylene glycol (antifreeze) poisoning?

1. AFomepizole
2. BAtropine
3. CFlumazenil
4. DNaloxone

Which drug is the antidote for paracetamol (acetaminophen) overdose?

1. AAcetylcysteine
2. BVitamin K
3. CFlumazenil
4. DNaloxone

A patient must mix regular (soluble) insulin and NPH (isophane) insulin in one syringe. What is the correct order?

1. ADraw up the cloudy NPH insulin first, then the clear regular insulin
2. BDraw up the clear regular insulin first, then the cloudy NPH insulin
3. CDraw them up in separate syringes, then mix them in a cup
4. DShake both vials hard, then draw them up in any order

During an infusion of a vesicant chemotherapy drug, the patient reports burning, and the site is swollen. What should the nurse do first?

1. AStop the infusion, leave the cannula in and follow the protocol
2. BFlush the line with a large volume of saline
3. CRemove the cannula at once and massage the area firmly
4. DIncrease the infusion rate to finish quickly

Какой признак типичен для опиоидной интоксикации?

1. AВысокая температура тела
2. BТочечные зрачки
3. CЧастое глубокое дыхание
4. DСильно расширенные зрачки

A patient on valproate becomes lethargic, starts vomiting and develops jaundice. Which adverse effect should be suspected first?

1. AKidney stones
2. BLiver toxicity
3. CHypothyroidism
4. DNormal start-up side effects

Why is pethidine (meperidine) avoided in older people and in kidney impairment?

1. AIt has no pain-relieving effect in older people
2. BIt is not absorbed from the gut when kidney function is poor
3. CIt causes severe hypoglycaemia in these groups
4. DIts metabolite norpethidine builds up and can cause seizures