Фармакология: лист заданий с ответами

Celecoxib selectively inhibits which enzyme?

1. ACyclo-oxygenase-2 (COX-2)
2. BLipoxygenase
3. CPhospholipase A2
4. DCyclo-oxygenase-1 (COX-1)

Naltrexone helps in alcohol use disorder because it:

1. ACauses vomiting and flushing whenever alcohol is drunk
2. BSpeeds up the liver breakdown of alcohol
3. CReplaces alcohol as a sedative
4. DBlocks opioid receptors, reducing reward and craving

Where should an adrenaline (epinephrine) auto-injector be given?

1. AInto a vein in the arm
2. BInto the outer thigh muscle
3. CUnder the tongue
4. DInto the abdomen under the skin

A patient with insulin-treated diabetes is found unconscious with very low blood glucose. There is no IV access. Which drug can a trained helper give?

1. AGlucagon by injection or nasal spray
2. BOral glucose gel poured into the mouth
3. CIntramuscular adrenaline
4. DRapid-acting insulin under the skin

Long-term use of metformin can cause a deficiency of which vitamin?

1. AVitamin K
2. BVitamin B12
3. CVitamin A
4. DVitamin D

An IV site is cool, swollen and pale, and the infusion is running slowly. What should the nurse do?

1. AApply a tight bandage over the site
2. BStop the infusion, remove the cannula and elevate the limb
3. CFlush the cannula forcefully with saline
4. DIncrease the infusion rate to push through and clear the blockage

A nurse calculates a child's dose and finds it is ten times higher than the usual range in the drug reference. What should the nurse do?

1. AGive the dose, because the prescriber is responsible for the order
2. BGive half the dose as a compromise
3. CWithhold it, recheck the calculation and clarify with the prescriber
4. DGive one tenth of the dose without telling anyone

Женщина, принимающая комбинированные оральные контрацептивы, начинает принимать карбамазепин от эпилепсии. Что вызывает главное опасение?

1. AОпасений нет, поскольку препараты не взаимодействуют
2. BИнтоксикация карбамазепином, поскольку таблетки сильно блокируют его метаболизм
3. CНеэффективность контрацепции, поскольку гормоны метаболизируются быстрее
4. DТяжёлая гипогликемия из-за этого сочетания