Фармакология: лист заданий с ответами

Celecoxib selectively inhibits which enzyme?

1. ACyclo-oxygenase-1 (COX-1)
2. BCyclo-oxygenase-2 (COX-2)
3. CPhospholipase A2
4. DLipoxygenase

What does "bacteriostatic" mean?

1. AThe drug prevents the patient's immune response
2. BThe drug kills viruses as well as bacteria
3. CThe drug stops bacteria multiplying without killing them directly
4. DThe drug kills bacteria directly by breaking down their cell wall

Which opioid receptor is mainly responsible for the pain relief and respiratory depression of morphine?

1. AKappa receptor
2. BDelta receptor
3. CMu receptor
4. DNicotinic receptor

An Rh-negative mother gives birth to an Rh-positive baby. When is anti-D immunoglobulin usually given?

1. AOnly at the start of the next pregnancy
2. BWithin 72 hours after the birth
3. CAt least two weeks after the birth
4. DIt is not needed if the baby is Rh-positive

A patient takes isoniazid. Which advice is most important?

1. ATake it with antacids to protect the stomach from irritation
2. BAvoid alcohol and report jaundice, dark urine or poor appetite
3. CExpect the urine to turn orange
4. DStop the drug when the cough improves

Which signs suggest early lithium toxicity?

1. APinpoint pupils and slow breathing
2. BVery high blood pressure and a severe headache
3. CHair loss and dark urine only
4. DDiarrhoea, vomiting, coarse tremor and drowsiness

Why is glibenclamide (glyburide) generally avoided in older adults?

1. AIt causes high blood glucose in older adults
2. BIt is long-acting and can cause prolonged, severe hypoglycaemia
3. CIt is not absorbed in people over 65
4. DIt causes severe weight loss and muscle wasting in older people

Why are antipsychotics used with great caution in older people with dementia?

1. AThey are linked to a higher risk of stroke and death
2. BThey are not absorbed in people over 65
3. CThey cause severe hypoglycaemia in older people
4. DThey always cure the dementia and stop all behaviour problems