Фармакология: лист заданий с ответами

How does allopurinol prevent gout?

1. AIt dissolves crystals already in the joint within hours
2. BIt inhibits xanthine oxidase, so less uric acid is made
3. CIt increases the kidney excretion of calcium
4. DIt blocks prostaglandins in the inflamed joint

Which adverse effect can follow long-term use of strong topical corticosteroids?

1. APermanent darkening of the nails
2. BThickening of the skin
3. CIncreased hair loss on the scalp
4. DThinning of the skin

Какой белок плазмы связывает большинство кислых лекарств, например варфарин?

1. AИнсулин
2. BГемоглобин
3. CФибриноген
4. DАльбумин

Benzathine benzylpenicillin (penicillin G benzathine) is ordered. Which route is correct?

1. ASubcutaneous in the abdomen
2. BDeep intramuscular only
3. CIntravenous infusion over 30 minutes
4. DIntravenous push

Long-term use of metformin can cause a deficiency of which vitamin?

1. AVitamin A
2. BVitamin B12
3. CVitamin K
4. DVitamin D

A person who has never been vaccinated against tetanus has a deep, dirty wound. What is usually given?

1. AOral antibiotics only
2. BTetanus vaccine only, after the wound heals
3. CNo treatment unless symptoms appear
4. DTetanus vaccine and tetanus immunoglobulin

Which statement about raloxifene for postmenopausal osteoporosis is correct?

1. AIt acts like oestrogen on bone but blocks oestrogen in the breast, and raises clot risk
2. BIt is a bisphosphonate taken weekly with water
3. CIt has no effect on the risk of blood clots
4. DIt acts like oestrogen in all tissues, including the breast, and relieves hot flushes

A drug is ordered at 5 micrograms/kg/min for an 80 kg patient. The infusion contains 1,600 micrograms per mL. What rate in mL/h is needed?

1. A15 mL/h
2. B25 mL/h
3. C4 mL/h
4. D150 mL/h