Фармакология: лист заданий с ответами

Alendronate, used for osteoporosis, belongs to which class?

1. ACorticosteroids
2. BBisphosphonates
3. CCalcium channel blockers
4. DThyroid hormones

Mannitol is an osmotic diuretic used mainly to:

1. APrevent blood clots
2. BReduce raised intracranial pressure
3. CTreat high blood pressure long term
4. DRaise serum potassium

Какой орган метаболизирует большинство лекарств?

1. AПочка
2. BЛёгкое
3. CСелезёнка
4. DПечень

Which description fits tardive dyskinesia?

1. AInvoluntary movements of the lips, tongue and face after long-term antipsychotic use
2. BA sudden painful spasm of the neck muscles and upward rolling of the eyes within days of the first dose
3. CHigh fever with lead-pipe rigidity and confusion
4. DA low white cell count with sore throat and fever

A patient starting sulfasalazine should be told about which harmless effect?

1. ABlue colouring of the tongue and gums
2. BWhite spots on the nails
3. CGreen colouring of the sweat
4. DOrange-yellow colouring of the urine

A child weighing 20 kg is prescribed a drug at 15 mg/kg per dose. What is the dose?

1. A35 mg
2. B300 mg
3. C150 mg
4. D3000 mg

An older patient who has taken omeprazole for many years has muscle cramps, tremor and an irregular heartbeat. Which lab finding is most likely linked to the drug?

1. ALow serum glucose
2. BHigh serum sodium
3. CHigh serum calcium
4. DLow serum magnesium

Какое свойство повышает вероятность прохождения лекарства через гематоэнцефалический барьер?

1. AБольшая молекулярная масса и сильное связывание с белками
2. BВысокая водорастворимость и сильная ионизация
3. CПоложительный заряд при физиологическом pH
4. DВысокая жирорастворимость и малый размер