Фармакология: лист заданий с ответами

Статины, например аторвастатин, снижают холестерин, ингибируя какой фермент?

1. AЦиклооксигеназу
2. BАнгиотензинпревращающий фермент
3. CЛипопротеинлипазу
4. DГМГ-КоА-редуктазу

Which description fits insulin glargine?

1. AA rapid-acting insulin given with each meal
2. BAn oral tablet that makes the pancreas release insulin
3. CA long-acting basal insulin with no marked peak
4. DAn intermediate-acting cloudy insulin with a clear peak

Epoetin alfa, often used in chronic kidney disease, stimulates the production of:

1. AClotting factors
2. BPlatelets
3. CWhite blood cells
4. DRed blood cells

During an amphotericin B infusion, the patient has fever, chills and shaking. What is the most likely explanation?

1. AA common infusion reaction to amphotericin B
2. BA sign that the drug has been given into an artery
3. CA sign that the fungal infection is cured
4. DSevere hypoglycaemia caused by the drug

Какой нежелательный эффект типичен для метоклопрамида, особенно у молодых людей?

1. AЭкстрапирамидные двигательные нарушения, например острая дистония
2. BНизкая глюкоза крови
3. CСухой кашель
4. DТяжёлый запор

During adult cardiac arrest, how often is IV adrenaline (epinephrine) usually repeated?

1. AOnce only, at the start
2. BEvery 15–20 minutes
3. CEvery 30 seconds
4. DEvery 3–5 minutes

A patient taking sertraline starts St John's wort for low mood. What is the main concern?

1. ASerotonin syndrome from combined serotonergic effects
2. BSevere low blood pressure from blocked alpha receptors
3. CBleeding from vitamin K deficiency
4. DA hypertensive crisis from tyramine

A patient who takes clonidine stopped it suddenly two days ago. He is now agitated, has a headache and his blood pressure is very high. What is the most likely explanation?

1. ANormal variation unrelated to the medication
2. BClonidine toxicity due to slow excretion by the kidneys
3. CRebound hypertension from abrupt clonidine withdrawal
4. DAn allergic reaction to clonidine