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Ім’я: ____________________ Дата: ____________
1.Легка
What is a prodrug?
AA drug that has passed all clinical trials
BA drug that is given before surgery
CA drug that is inactive until the body converts it into its active form
DA drug that prevents or reverses the effect of another drug in the body
2.Легка
Donepezil, used in Alzheimer's disease, belongs to which class?
ASelective serotonin reuptake inhibitors
BAcetylcholinesterase inhibitors
CDopamine agonists
DBenzodiazepines
3.Легка
Чому деяким людям із хворобами серця призначають ацетилсаліцилову кислоту в низькій дозі?
AЩоб сповільнити серцебиття
BЩоб знизити рівень холестерину в крові та стабілізувати бляшки
CЩоб зменшити агрегацію тромбоцитів і запобігти тромбам
DЩоб негайно зняти біль у грудях
4.Середня
Why is a spacer recommended with a metered-dose inhaler?
AMore drug reaches the lungs and less stays in the mouth
BIt doubles the dose of drug released by each puff of the inhaler
CIt removes the need to shake the inhaler
DIt turns the inhaler into a nebuliser
5.Середня
A patient given haloperidol develops a sudden painful twisting of the neck and the eyes roll upward. Which drug is usually given?
ANaloxone
BAn anticholinergic such as benzatropine (benztropine)
CA second dose of haloperidol
DDantrolene by mouth to relax the twisted neck muscles
6.Середня
How should a hyoscine (scopolamine) patch for motion sickness be used?
AApply it behind the ear several hours before travel
BSwallow it if no water is available
CApply it to the chest only after the vomiting has started
DCut it in half for children without advice
7.Складна
Which regimen is standard for eradicating Helicobacter pylori?
AAn H2 blocker taken only when pain occurs
BAcid suppression plus at least two antibiotics, often with bismuth, for 14 days
CAn antacid alone, taken after meals and at bedtime for six months
DA single dose of an antibiotic given intravenously
8.Складна
A patient with severe liver cirrhosis needs a benzodiazepine for alcohol withdrawal. Why is lorazepam often chosen instead of diazepam?
ALorazepam is excreted unchanged in the urine without any metabolism
BLorazepam is a stronger anticonvulsant than all other benzodiazepines
CLorazepam does not cause sedation in liver disease
DLorazepam is cleared by simple conjugation and has no active metabolites
Ключ відповідей
1. C · A drug that is inactive until the body converts it into its active form
2. B · Acetylcholinesterase inhibitors
3. C · Щоб зменшити агрегацію тромбоцитів і запобігти тромбам
4. A · More drug reaches the lungs and less stays in the mouth
5. B · An anticholinergic such as benzatropine (benztropine)
6. A · Apply it behind the ear several hours before travel
7. B · Acid suppression plus at least two antibiotics, often with bismuth, for 14 days
8. D · Lorazepam is cleared by simple conjugation and has no active metabolites
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