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Ім’я: ____________________ Дата: ____________
1.Легка
Giving a patient immunoglobulin after exposure to an infection provides which type of immunity?
AInnate immunity
BActive immunity
CHerd immunity
DPassive immunity
2.Легка
Which of these drugs has a narrow therapeutic index?
ALoratadine
BAmoxicillin
COmeprazole
DLithium
3.Легка
What is a prodrug?
AA drug that prevents or reverses the effect of another drug in the body
BA drug that has passed all clinical trials
CA drug that is inactive until the body converts it into its active form
DA drug that is given before surgery
4.Середня
Why is hypovolaemia corrected with IV fluids before or while starting a vasopressor?
AVasopressors only work when they are diluted in large fluid volumes
BVasopressors cannot keep perfusion up if the circulation is under-filled
CVasopressors cause the patient to retain too much fluid
DFluids stop the vasopressor causing a fever
5.Середня
Which advice helps reduce the most common side effect of varenicline?
ATake it with alcohol to reduce nausea
BTake it after food with a full glass of water
CTake it on an empty stomach at bedtime with a little milk
DTake double doses in the first week
6.Середня
Чому пацієнтам, які приймають клозапін, потрібні регулярні аналізи крові?
AВін часто спричиняє залізодефіцитну анемію
BВін небезпечно підвищує кількість тромбоцитів
CВін змінює групу крові
DВін може спричинити агранулоцитоз
7.Складна
A patient on long-term lithium passes large amounts of dilute urine and is always thirsty. What is the most likely explanation?
ALithium causes type 1 diabetes by destroying the pancreatic beta cells
BLithium increases ADH release from the pituitary
CThe patient is drinking too much and lithium is unrelated
DLithium blocks the kidney's response to ADH (nephrogenic diabetes insipidus)
8.Складна
A patient on weekly methotrexate is prescribed trimethoprim for a urinary infection. What is the main risk?
ABone marrow suppression, because both drugs inhibit folate metabolism
BLoss of antibiotic effect because methotrexate binds trimethoprim
CSevere hypertension from the combination
DHypoglycaemia from reduced liver glucose output
Ключ відповідей
1. D · Passive immunity
2. D · Lithium
3. C · A drug that is inactive until the body converts it into its active form
4. B · Vasopressors cannot keep perfusion up if the circulation is under-filled
5. B · Take it after food with a full glass of water
6. D · Він може спричинити агранулоцитоз
7. D · Lithium blocks the kidney's response to ADH (nephrogenic diabetes insipidus)
8. A · Bone marrow suppression, because both drugs inhibit folate metabolism
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