1.简单
抗生素对什么有效?
- A病毒
- B过敏反应
- C所有微生物同样有效
- D细菌
2.简单
Why is folinic acid (leucovorin) given after high-dose methotrexate?
- ATo treat an allergic reaction to methotrexate
- BTo make methotrexate act faster on the tumour
- CTo protect normal cells from methotrexate toxicity
- DTo prevent nausea and vomiting after the methotrexate
3.简单
Venlafaxine belongs to which class of antidepressants?
- ATricyclic antidepressants
- BSelective serotonin reuptake inhibitors (SSRIs)
- CSerotonin–noradrenaline reuptake inhibitors (SNRIs)
- DMonoamine oxidase inhibitors
4.中等
A patient takes isoniazid. Which advice is most important?
- AAvoid alcohol and report jaundice, dark urine or poor appetite
- BExpect the urine to turn orange
- CTake it with antacids to protect the stomach from irritation
- DStop the drug when the cough improves
5.中等
Why is a progestogen added to oestrogen in hormone replacement therapy for a woman who still has her uterus?
- ATo prevent breast cancer completely
- BTo reduce hot flushes much more than oestrogen alone can
- CTo lower the risk of blood clots to zero
- DTo protect against endometrial hyperplasia and cancer
6.中等
During a rapid infusion of vancomycin, a patient develops flushing and a red rash on the face, neck and upper body. What is the most likely cause and action?
- AA normal effect; increase the infusion rate to finish sooner
- BA sign that the infection is spreading; give a second dose
- CAcute kidney failure; stop all IV fluids and antibiotics at once
- DAn infusion reaction; stop or slow the infusion and inform the prescriber
7.困难
A patient with heart failure starts taking naproxen regularly for back pain. Why is this a concern?
- ANSAIDs increase heart contractility too much
- BNSAIDs cause salt and water retention and can worsen heart failure
- CNSAIDs lower potassium, which makes digoxin and diuretics fail
- DNSAIDs block the absorption of furosemide completely
8.困难
Which regimen is standard for eradicating Helicobacter pylori?
- AAn antacid alone, taken after meals and at bedtime for six months
- BAcid suppression plus at least two antibiotics, often with bismuth, for 14 days
- CA single dose of an antibiotic given intravenously
- DAn H2 blocker taken only when pain occurs
答案
- 1. D · 细菌
- 2. C · To protect normal cells from methotrexate toxicity
- 3. C · Serotonin–noradrenaline reuptake inhibitors (SNRIs)
- 4. A · Avoid alcohol and report jaundice, dark urine or poor appetite
- 5. D · To protect against endometrial hyperplasia and cancer
- 6. D · An infusion reaction; stop or slow the infusion and inform the prescriber
- 7. B · NSAIDs cause salt and water retention and can worsen heart failure
- 8. B · Acid suppression plus at least two antibiotics, often with bismuth, for 14 days
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