1.简单
哪个器官主要负责代谢大多数药物?
- A肝脏
- B肺
- C脾脏
- D肾脏
2.简单
什么是拮抗剂?
- A增加神经末梢释放天然配体的药物
- B完全激活受体的药物
- C转化为活性形式的药物
- D与受体结合但不激活受体、并阻断激动剂的药物
3.简单
What is the normal serum sodium range in adults?
- A95–105 mmol/L
- B135–145 mmol/L
- C150–165 mmol/L
- D3.5–5.0 mmol/L
4.中等
阿米替林等三环类抗抑郁药过量为什么特别危险?
- A心律失常和癫痫发作
- B血糖突然升高
- C肾结石
- D数小时内发生严重肝衰竭
5.中等
哪个因素会增加锂中毒的风险?
- A随餐服药
- B高盐饮食
- C脱水
- D多喝水
6.中等
Which teaching about antiepileptic drugs is most important?
- AAlcohol has no effect on seizure control
- BDo not stop the drug suddenly, as this can trigger severe seizures
- CStop the drug when you have had no seizures for one whole week
- DTake a double dose if you feel a seizure coming
7.困难
A patient receiving a phenylephrine infusion has a rise in blood pressure and a fall in heart rate. What is the best explanation?
- AThe fall in heart rate shows phenylephrine toxicity of the AV node
- BPhenylephrine directly blocks beta-1 receptors in the heart's conduction system
- CAlpha-1 vasoconstriction raises blood pressure and causes reflex bradycardia
- DPhenylephrine stimulates muscarinic receptors
8.困难
A patient who has taken lorazepam daily for many months stops it suddenly. Which serious complication may follow?
- AProfound respiratory depression
- BPinpoint pupils and coma
- CSevere bradycardia
- DWithdrawal seizures
答案
- 1. A · 肝脏
- 2. D · 与受体结合但不激活受体、并阻断激动剂的药物
- 3. B · 135–145 mmol/L
- 4. A · 心律失常和癫痫发作
- 5. C · 脱水
- 6. B · Do not stop the drug suddenly, as this can trigger severe seizures
- 7. C · Alpha-1 vasoconstriction raises blood pressure and causes reflex bradycardia
- 8. D · Withdrawal seizures
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