药理学练习卷（附答案）

Celecoxib selectively inhibits which enzyme?

1. APhospholipase A2
2. BCyclo-oxygenase-2 (COX-2)
3. CCyclo-oxygenase-1 (COX-1)
4. DLipoxygenase

Tamoxifen is used mainly to treat:

1. AType 2 diabetes
2. BOestrogen receptor-positive breast cancer
3. CProstate enlargement and prostate cancer in older men
4. DOsteoarthritis

How does rasagiline help in Parkinson's disease?

1. AIt inhibits MAO-B, so brain dopamine is broken down more slowly
2. BIt blocks dopamine receptors in the brain
3. CIt is converted directly into dopamine inside brain neurones
4. DIt blocks acetylcholine receptors in the gut

Which assessment is most important before giving a dose of IV morphine?

1. ABowel sounds and urine colour
2. BRespiratory rate and level of sedation
3. CPupil size and hearing
4. DBlood glucose and temperature, checked before each dose

A patient is starting lamotrigine. Which adverse effect should the patient report at once?

1. AMild headache on the first day
2. BA brief change in taste
3. CAny new skin rash
4. DSlight tiredness in the afternoon

哪种副作用是钙通道阻滞剂氨氯地平的典型副作用？

1. A干咳
2. B支气管痉挛
3. C踝部水肿
4. D高钾血症

A patient taking hydralazine for several months develops joint pain, fever and a rash. Anti-histone antibodies are positive. What is the most likely diagnosis?

1. AAn acute viral infection
2. BRheumatoid arthritis
3. CGout
4. DDrug-induced lupus

Before starting rituximab, patients are tested for hepatitis B. Why?

1. ARituximab can reactivate hepatitis B and cause liver failure
2. BHepatitis B infection makes rituximab completely ineffective
3. CRituximab is made from the hepatitis B virus
4. DRituximab is a vaccine against hepatitis B