1.简单
Which of these is a second-generation (atypical) antipsychotic?
- AChlorpromazine
- BHaloperidol
- CFluphenazine
- DOlanzapine
2.简单
How do second-generation antihistamines such as cetirizine and loratadine differ from older ones?
- AThey are given only by injection
- BThey block H2 receptors in the stomach
- CThey work only on the skin
- DThey cause much less drowsiness
3.简单
什么是激动剂?
- A加快自身排泄的药物
- B与受体结合并阻断受体的药物
- C破坏受体的药物
- D与受体结合并激活受体的药物
4.中等
哪个因素会增加锂中毒的风险?
- A随餐服药
- B脱水
- C多喝水
- D高盐饮食
5.中等
A patient given haloperidol develops a sudden painful twisting of the neck and the eyes roll upward. Which drug is usually given?
- ADantrolene by mouth to relax the twisted neck muscles
- BA second dose of haloperidol
- CAn anticholinergic such as benzatropine (benztropine)
- DNaloxone
6.中等
Why are patients taking simvastatin often advised to avoid large amounts of grapefruit juice?
- AGrapefruit speeds up simvastatin breakdown in the liver, so the drug stops working
- BGrapefruit inhibits CYP3A4 in the gut, raising simvastatin levels and myopathy risk
- CGrapefruit blocks cholesterol absorption and causes low cholesterol
- DGrapefruit makes the tablet dissolve in the mouth
7.困难
Carboprost is a prostaglandin used for postpartum haemorrhage. In which woman should it be avoided?
- AA woman with asthma
- BA woman who had a vaginal birth
- CA woman who is breastfeeding
- DA woman with iron deficiency anaemia
8.困难
A patient who has taken lorazepam daily for many months stops it suddenly. Which serious complication may follow?
- AWithdrawal seizures
- BPinpoint pupils and coma
- CSevere bradycardia
- DProfound respiratory depression
答案
- 1. D · Olanzapine
- 2. D · They cause much less drowsiness
- 3. D · 与受体结合并激活受体的药物
- 4. B · 脱水
- 5. C · An anticholinergic such as benzatropine (benztropine)
- 6. B · Grapefruit inhibits CYP3A4 in the gut, raising simvastatin levels and myopathy risk
- 7. A · A woman with asthma
- 8. A · Withdrawal seizures
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