1.简单
什么是药物耐受性?
- A服用药物而完全不产生任何副作用的能力
- B对药物的过敏反应
- C每次服药反应都更强
- D反复使用后反应减弱,因此需要更大剂量
2.简单
Why do nurses wear chemotherapy-tested gloves and gowns when handling cytotoxic drugs?
- ATo keep the drugs warm during the infusion
- BTo protect the drug from light
- CBecause cytotoxic drugs are radioactive and give off radiation
- DTo avoid exposure to drugs that may cause cancer or birth defects
3.简单
Why is magnesium sulfate given to a woman with severe pre-eclampsia?
- ATo prevent eclamptic seizures
- BTo treat a urinary infection
- CTo raise her blood pressure
- DTo start labour contractions
4.中等
Why is testing for HLA-B*15:02 recommended before carbamazepine in people of some Asian ancestries?
- AThis gene variant causes carbamazepine to raise blood glucose
- BIt greatly raises the risk of Stevens–Johnson syndrome
- CThis gene variant speeds up the kidney excretion of carbamazepine
- DThis gene variant makes carbamazepine ineffective
5.中等
Methylergometrine (methylergonovine) is prescribed for postpartum bleeding. Which finding would make the nurse withhold it and check with the prescriber?
- ABlood pressure of 160/105 mmHg
- BTemperature of 37.2 °C (99 °F)
- CHeart rate of 88 per minute
- DHaemoglobin slightly below normal
6.中等
Why is aspirin avoided in children and teenagers with viral illnesses such as flu or chickenpox?
- AIt stops the vaccine from working
- BIt is linked to Reye's syndrome, which harms the liver and brain
- CIt causes severe, permanent hearing loss in young children
- DIt causes grey baby syndrome
7.困难
A patient receives high-dose IV aciclovir for herpes encephalitis. Which nursing action reduces the main risk to the kidneys?
- ARestrict oral and IV fluids to prevent brain swelling
- BGive the infusion as a rapid push
- CKeep the patient well hydrated and give the infusion slowly
- DGive a loop diuretic before each dose
8.困难
Why is gentamicin often given once daily instead of in several small doses?
- AIt is absorbed slowly from the muscle over 24 hours
- BIt has a very long half-life of several days
- CIts killing depends only on the time the level stays above the MIC
- DIts killing depends on high peak levels, with a post-antibiotic effect
答案
- 1. D · 反复使用后反应减弱,因此需要更大剂量
- 2. D · To avoid exposure to drugs that may cause cancer or birth defects
- 3. A · To prevent eclamptic seizures
- 4. B · It greatly raises the risk of Stevens–Johnson syndrome
- 5. A · Blood pressure of 160/105 mmHg
- 6. B · It is linked to Reye's syndrome, which harms the liver and brain
- 7. C · Keep the patient well hydrated and give the infusion slowly
- 8. D · Its killing depends on high peak levels, with a post-antibiotic effect
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