药理学练习卷（附答案）

Disulfiram is used in alcohol use disorder because it:

1. ACauses an unpleasant reaction if alcohol is drunk
2. BCures liver damage caused by alcohol
3. CRemoves alcohol from the blood faster
4. DReplaces alcohol at its receptors in the brain

Celecoxib selectively inhibits which enzyme?

1. ACyclo-oxygenase-1 (COX-1)
2. BPhospholipase A2
3. CLipoxygenase
4. DCyclo-oxygenase-2 (COX-2)

Which signs are typical of hypoglycaemia?

1. AFruity breath with deep, rapid breathing
2. BThirst, frequent urination and warm, dry, flushed skin
3. CSweating, shakiness, a fast heart rate and confusion
4. DA slow pulse, constipation and weight gain

为什么多西环素不应与牛奶或抗酸药同时服用？

1. A钙和其他金属离子会与之结合，减少吸收
2. B牛奶通过诱导酶加快其在肝脏中的分解
3. C抗酸药会把它变成有毒化合物
4. D合用会引起严重便秘

Benzathine benzylpenicillin (penicillin G benzathine) is ordered. Which route is correct?

1. ADeep intramuscular only
2. BSubcutaneous in the abdomen
3. CIntravenous infusion over 30 minutes
4. DIntravenous push

A transplant patient takes tacrolimus. Which monitoring is most important?

1. ASerum amylase
2. BBlood drug levels and kidney function
3. CPeak expiratory flow
4. DThyroid function and bone density

A patient taking azathioprine is prescribed allopurinol for gout. What is the main danger?

1. AGout becomes worse because allopurinol is inactivated by azathioprine
2. BSevere bone marrow suppression, because azathioprine breakdown is reduced
3. CSevere hypertension from the combination
4. DLiver enzyme induction, making azathioprine ineffective

A patient on lisinopril for hypertension starts taking ibuprofen every day for knee pain. What is the main concern?

1. AA large fall in blood pressure, with fainting and falls on standing up
2. BWeaker blood pressure control, kidney injury and high potassium
3. CA higher risk of a dry cough than with lisinopril alone
4. DFaster liver metabolism of lisinopril, so it stops working